GTP结合蛋白4抗体
规格：1mg/1ml
英文名： GTPBP4
别名： Chronic renal failure gene protein; CRFG; G protein binding protein CRFG; GTP binding protein 4; NGB; NOG1; Nucleolar GTP binding protein 1; NOG1_HUMAN.
分子量： 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GTPBP4/C
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
GTP结合蛋白4抗体产品介绍：background: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [Entrez Gene] Function: Involved inGTP结合蛋白4抗体 the biogenesis of the 60S ribosomal subunit Subcellular Location: Nucleus, nucleolus. Similarity: Belongs to the GTP1/OBG family. NOG subfamily. Gene ID: 23560 Database links: Entrez Gene: 23560 Human Entrez Gene: 69237 Mouse Entrez Gene:GTP结合蛋白4抗体 114300 Rat SwissProt: Q9BZE4 Human SwissProt: Q99ME9 Mouse SwissProt: Q99P77 Rat Unigene: 215766 Human Unigene: 41800 Mouse Unigene: 96111 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GTP结合蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid