钙调蛋白结合转录激活因子1抗体
规格:1mg/1ml
英文名: CAMTA1
别名: Calmodulin-binding transcription activator 1; Calmodulin binding transcription activator 1; CMTA1; KIAA0833; CMTA1_HUMAN.
分子量: 183kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CAMTA1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
钙调蛋白结合转录激活因子1抗体细胞定位:细胞核 细胞浆
产品介绍:background: CAMTA1 is a transcription activator which is a putatuove tumor suppressor. It is thought to interact with calmodulin. Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma. Function: Transcriptional activator. May act as a tumor suppressor. Subunit: May interact with calmodulin (Potential). Subcellular Location: Nucleus (Probable). Cytoplasm. Tissue Specificity: Normally expressed in non-neoplastic ***** central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astro钙调蛋白结合转录激活因子1抗体cytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. Expressed in heart and kidney. Similarity: Belongs to the CAMTA family. Contains 3 ANK repeats. Contains 1 CG-1 DNA-binding domain.钙调蛋白结合转录激活因子1抗体 Contains 1 IPT/TIG domain. Contains 3 IQ domains. Database links: UniProtKB/Swiss-Prot: Q9Y6Y1.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产钙调蛋白结合转录激活因子1抗体品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid