原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体
规格：1mg/1ml
英文名： MOCOS
别名： c mos; c-mos; MSV; y Oocyte maturation factor mos; Proto oncogene serine / threonine protein kinase mos; FLJ20733; HMCS; MCS; MoCo sulfurase; Molybdenum cofactor sulfurase; MOS; v mos Moloney murine s
分子量： 98kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MOCOS
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：细胞浆
原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体产品介绍：background: MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742]).[supplied by OMIM, Feb 2010] Function: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. DISEASE: Defects in MOCOS are the cause of xanthinuria type 2 (XU2) [MIM:603592]. Xanthinuria is 原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. In addition, patient suffering of XU2 cannot metabolize allopurinol into oxypurinol due to dual deficiency of xanthine dehydrogenase and aldehyde oxidase. Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily. Contains 1 MOSC domain. Gene ID: 55034 Database links: Entrez Gene: 55034 Human Omim: 613274 Human原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体SwissProt: Q96EN8 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原癌基因丝氨酸/苏氨酸蛋白激酶MOS抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学 染色质和核信号 干细胞 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid