鳞状细胞癌增强蛋白1抗体
规格：1mg/1ml
英文名： GASC1/KDM4C
别名： GASC 1 protein; GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain containing histone demethylation protein 3C; Jumonji domain containing protein 2C; KDM4C; KDM4C_
分子量： 120kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KDM4C/GA
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
鳞状细胞癌增强蛋白1抗体产品介绍：background: KDM4C/JMJD2C, a jumonji domain containing protein, is a histone demethylase. JMJD2C specifically demethylates Lysine 9 and Lysine 36 residues of Histone H3, thereby playing a central role in regulating histone modifications. Function: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 鳞状细胞癌增强蛋白1抗体'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Subcellular Location: Nucleus (By similarity). Tissue Specificity: Overexpressed in several esophageal squamous cell carcinomas (ESCs). Similarity: Belongs to the JHDM3 histone demethylase family. Contains 1 JmjC domain. Contains 1 JmjN 鳞状细胞癌增强蛋白1抗体domain. Contains 2 PHD-type zinc fingers. Contains 2 Tudor domains. Database links: UniProtKB/Swiss-Prot: Q9H3R0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
鳞状细胞癌增强蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid