TWIK相关酸敏感钾离子通道蛋白9抗体
规格:1mg/1ml
英文名: KCNK9
别名: KCNK 9; KCNK-9; TASK3; Potassium channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Short=Two
分子量: 40kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KCNK9
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
TWIK相关酸敏感钾离子通道蛋白9抗体产品介绍:background: KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents. Function: pH-dependent, voltage-insensitiveTWIK相关酸敏感钾离子通道蛋白9抗体, background potassium channel protein. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. DISEASE: Defects in KCNK9 are the cause of Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:612292]. A syndrome characterized by mental retardation, hypotonia, TWIK相关酸敏感钾离子通道蛋白9抗体hyperactivity, and facial dysmorphism. Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) Gene ID: 51305 Database links: Entrez Gene: 428382 Chicken Entrez Gene: 51305 Human Omim: 605874 Human SwissProt: Q9NPC2 Human Unigene: 493037 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TWIK相关酸敏感钾离子通道蛋白9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 神经生物学 通道蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid