纤维母细胞生长因子6抗体
规格：1mg/1ml
英文名： FGF6
别名： FGF 6; FGF6; FGF-6; Fibroblast growth factor 6; Fibroblast growth factor 6 precursor; HBGF 6; HBGF6; HST 2; HST2.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGF6
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ,d
细胞定位：细胞外基质 分泌型蛋白
纤维母细胞生长因子6抗体产品介绍：background: FGF6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. The FGF6 gene displays oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle纤维母细胞生长因子6抗体 regeneration or differentiation. Function: Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. Subunit: Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.纤维母细胞生长因子6抗体 Subcellular Location: Secreted, extracellular space. Tissue Specificity: Leukemia cell lines with platelet/ megakaryocytic differentiation potential. Similarity: Belongs to the heparin-binding growth factors family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纤维母细胞生长因子6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid