碱性成纤维细胞生长因子9抗体
规格：1mg/1ml
英文名： FGF9
别名： FGF 9; FGF-9; FGF9; FGF9_HUMAN; Fibroblast growth factor 9; GAF; Glia Activating Factor; Glia-activating factor; HBFG 9; HBFG9; HBGF-9; Heparin-binding growth factor 9; MGC119914; MGC119915.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGF9
交叉反应：Human, Mouse, Rat, Chicken, Dog,
细胞定位：分泌型蛋白
碱性成纤维细胞生长因子9抗体产品介绍：background: May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Function: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Subunit: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Glial cells. Post-translational modifications: Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore,碱性成纤维细胞生长因子9抗体 there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step. DISEASE: Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3) [MIM:612961]. Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Similarity: Belongs to the heparin-binding growth factors family. Gene ID: 2254 Database links: Entrez Gene: 378917 Chicken 碱性成纤维细胞生长因子9抗体Entrez Gene: 2254 Human Entrez Gene: 14180 Mouse Entrez Gene: 396717 Pig Entrez Gene: 25444 Rat Omim: 600921 Human SwissProt: P31371 Human SwissProt: P54130 Mouse SwissProt: Q95L12 Pig SwissProt: P36364 Rat Unigene: 111 Human Unigene: 8846 Mouse Unigene: 25174 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碱性成纤维细胞生长因子9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 神经生物学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid