RNA结合基因蛋白3抗体
规格:1mg/1ml
英文名: RBM3
别名: Putative RNA binding protein 3; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; RNPL; RP23-27I6.7; RBM3_HUMAN.
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RBM3
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:细胞核 细胞浆
RNA结合基因蛋白3抗体产品介绍:background: This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]. Function: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphoryaltion of translation initiation factors and active polysome formation (By similarity).RNA结合基因蛋白3抗体 Subunit: Interacts with RPL4. Associates with the 60S ribosomal subunits in an RNA-independent manner. Associates with ribosomes. Subcellular Location: Nucleus. Cytoplasm. Cell projection, dendrite. Post-translational modifications: Arg-105 isRNA结合基因蛋白3抗体 dimethylated, probably to asymmetric dimethylarginine. Phosphorylated (By similarity). Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: P98179.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合基因蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid