胶原三股螺旋重复蛋白1抗体
规格：1mg/1ml
英文名： CTHRC1
别名： Collagen triple helix repeat containing 1; Collagen triple helix repeat containing protein 1; Collagen triple helix repeat-containing protein 1; CTHR1_HUMAN; Cthrc1; NMTC1 protein; Protein NMTC1.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CTHRC1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞外基质 分泌型蛋白
胶原三股螺旋重复蛋白1抗体产品介绍：background: CTHRC1 is a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. Function: May act as a negative regulator of collagen matrix deposition (By similarity). Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells. Post-translational modifications: N-glycosylated (By similarity). DISEASE: Barrett esophagus (BE) [MIM:614266]: A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is 胶原三股螺旋重复蛋白1抗体replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Similarity: Contains 胶原三股螺旋重复蛋白1抗体1 collagen-like domain. Database links: UniProtKB/Swiss-Prot: Q96CG8.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胶原三股螺旋重复蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学 信号转导 生长因子和** 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid