瞬时表达轴索糖蛋白1抗体
规格:1mg/1ml
英文名: TAG1
别名: Axonal glycoprotein TAG 1; Axonal glycoprotein TAG-1; Axonal glycoprotein TAG1; Axonin 1; Axonin-1; Axonin1; AXT; CNTN 2; Cntn2; CNTN2_HUMAN; contactin 2 (axonal); Contactin 2; Contactin-2; Contactin2
分子量: 107kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TAG1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
瞬时表达轴索糖蛋白1抗体产品介绍:background: Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic瞬时表达轴索糖蛋白1抗体 (Contactin 2/Contactin 2) binding site is localized to the FNIII domain. Function: May play a role in the initial growth and guidance of axons. May be involved in cell adhesion. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons. Similarity: Belongs to the immunoglobulin superfamily. Contactin family.瞬时表达轴索糖蛋白1抗体 Contains 4 fibronectin type-III domains. Contains 6 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: Q02246.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
瞬时表达轴索糖蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 神经生物学 生长因子和** 细胞粘附分子 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid