钙粘蛋白6抗体
规格:1mg/1ml
英文名: K Cadherin
别名: Cadherin 6; Cadherin6; Cadherin-6; Cadherin 6 type 2; Cadherin fetal kidney; Cadherin6; CDH 6; CDH6; KCAD; Kidney cadherin; CADH6_HUMAN.
分子量: 82kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human K Cadher
交叉反应:Human, Mouse, Rat, Cow, Horse,
细胞定位:细胞膜
钙粘蛋白6抗体产品介绍:background: K Cadherin (Cadherin 6) is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells. K Cadherin is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. It is also expressed in certain liver and kidney carcinomas. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves钙粘蛋白6抗体 in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. Similarity: Contains 5 cadherin domains. 钙粘蛋白6抗体Database links: UniProtKB/Swiss-Prot: P55285.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙粘蛋白6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-300 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid