凋亡抑制因子2抗体
规格：1mg/1ml
英文名： API2/BIRC3
别名： cIAP2; CIAP 2; CIAP-2; Inhibitor of apoptosis protein 1; AIP 1; AIP1; API 2; API2; Apoptosis inhibitor 2; Baculoviral IAP repeat containing 3; Baculoviral IAP repeat containing protein 3; Baculoviral
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human cIAP2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
凋亡抑制因子2抗体产品介绍：background: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Function: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Subunit: Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 凋亡抑制因子2抗体(TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). Interacts with RIP1, RIP2, RIP3, RIP4 and USP19. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highly expressed in fetal lung, and kidney. In the *****, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes. DISEASE: Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma. Similarity: Belongs to the凋亡抑制因子2抗体 IAP family. Contains 3 BIR repeats. Contains 1 CARD domain. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 330 Human Entrez Gene: 11796 Mouse Entrez Gene: 78971 Rat Omim: 601721 Human SwissProt: Q13489 Human SwissProt: O08863 Mouse Unigene: 127799 Human Unigene: 2026 Mouse Unigene: 64578 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凋亡抑制因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid