细胞因子诱导凋亡抑制因子1
规格：1mg/1ml
英文名： CIAPIN1
别名： Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CIAPIN1
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞核 细胞浆
细胞因子诱导凋亡抑制因子1产品介绍：background: CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1. Function: May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). 细胞因子诱导凋亡抑制因子1Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. 细胞因子诱导凋亡抑制因子1Highly expressed in heart, liver and pancreas. Similarity: Belongs to the anamorsin family. Database links: UniProtKB/Swiss-Prot: Q6FI81.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞因子诱导凋亡抑制因子1产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid