转化酸性卷曲含蛋白质2
规格：1mg/1ml
英文名： TACC2
别名： TACC2_HUMAN; Anti zuai 1; AZU 1; AZU1; ECTACC; TACC 2; Transforming acidic coiled coil containing protein 2.
分子量： 309kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TACC2
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：
转化酸性卷曲含蛋白质2产品介绍：background: TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin. Function: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors 转化酸性卷曲含蛋白质2(By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. Subunit: Interacts with CCDC100/CEP120 (By similarity). Interacts with microtubules. Interacts with YEATS4, GCN5L2 and PCAF. Subcellular Location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. Tissue Specificity: Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea. Post-translational modifications: Phosphorylated by TTK; which is required for localization in centrosome.转化酸性卷曲含蛋白质2 Similarity: Belongs to the TACC family. Contains 1 SPAZ (Ser/Pro-rich AZU-1) domain. Database links: UniProtKB/Swiss-Prot: O95359.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转化酸性卷曲含蛋白质2产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞周期蛋白 细胞分化 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid