蛋白酪氨酸磷酸酶相互作用蛋白51抗体
规格:1mg/1ml
英文名: TCPTP/PTPIP51
别名: Cerebral protein 10; Family with sequence similarity 82 member C; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51;
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PTPIP51/
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核 细胞浆
蛋白酪氨酸磷酸酶相互作用蛋白51抗体产品介绍:background: FAM82A2, or family with sequence similarity 82, member C, may participate in differentiation and apoptosis of keratinocytes. Overexpression of FAM82A2 induces apoptosis. Function: Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis. Subunit: Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB. Subcellular Location: Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Tissue Specificity: Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers 蛋白酪氨酸磷酸酶相互作用蛋白51抗体of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed蛋白酪氨酸磷酸酶相互作用蛋白51抗体. Similarity: Belongs to the RMDN family. Database links: Entrez Gene: 5771 Human Entrez Gene: 19255 Mouse Entrez Gene: 117063 Rat Omim: 176887 Human SwissProt: P17706 Human SwissProt: Q06180 Mouse SwissProt: P35233 Rat Unigene: 654527 Human Unigene: 663373 Human Unigene: 260433 Mouse Unigene: 33497 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酪氨酸磷酸酶相互作用蛋白51抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid