Ras相关区域家族蛋白4抗体
规格:1mg/1ml
英文名: RASSF4
别名: AD037; Ras association (RalGDS/AF 6) domain family 4; Ras association domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; RASSF 4; Tumor
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RASSF4
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:
Ras相关区域家族蛋白4抗体产品介绍:background: The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest. Subunit: Interacts directly Ras相关区域家族蛋白4抗体with activated KRAS in a GTP-dependent manner. Tissue Specificity: Widely expressed. Frequently down-regulated in tumor cell lines. Similarity: Contains 1 Ras-associating domain. Contains 1 SARAH domain. Gene ID: 83937 Database links: Entrez Gene: 83937 Human Entrez Gene: 213391 Mouse Entrez Gene: 362423 Rat Omim: 610559 Human SwissProt: Q9H2L5 Human SwissProt: Q8CB96 Ras相关区域家族蛋白4抗体Mouse SwissProt: Q566C5 Rat Unigene: 522895 Human Unigene: 257931 Mouse Unigene: 195253 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Ras相关区域家族蛋白4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 细胞周期蛋白 G蛋白偶联受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid