磷酸化14-3-3E蛋白抗体
规格:1mg/1ml
英文名: phospho-14-3-3 epsilon (Thr232)
别名: YWHAE(phospho T232); 14-3-3 epsilon (phospho Thr232); 14-3-3 epsilon; 14 3 3 E; 14 3 3 epsilon; 14 3 3E; 14-3-3 E; 14-3-3 protein epsilon; 14-3-3E; 1433E_HUMAN; KCIP 1; KCIP-1; KCIP1; MDCR; MDS; mitoc
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Cow, Sheep,
细胞定位:
产磷酸化14-3-3E蛋白抗体品介绍:background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Subunit: Homodimer. Heterodimerizes with YWHAZ. Interacts with NDEL1, RGNEF and TIAM2. Interacts with HCV core protein. Interacts with ABL1 (phosphorylated form); the interaction 磷酸化14-3-3E蛋白抗体retains it in the cytoplasm. Weakly interacts with CDKN1B. Interacts with GAB2. Interacts with phosphorylated GRB10. Interacts with PKA-phosphorylated AANAT. Interacts with the phosphorylated (by AKT1) form of SRPK2. Subcellular Location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Similarity: Belongs to the 14-3-3 family. Gene ID磷酸化14-3-3E蛋白抗体: 7531 Database links: Entrez Gene: 7531 Human Entrez Gene: 282125 Cow Entrez Gene: 22627 Mouse Entrez Gene: 29753 Rat Omim: 605066 Human SwissProt: P62261 Cow SwissProt: P62258 Human SwissProt: P62259 Mouse SwissProt: P62260 Rat Unigene: 513851 Human Unigene: 234700 Mouse Unigene: 471625 Mouse Unigene: 4225 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化14-3-3E蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 神经生物学 信号转导 干细胞 细胞凋亡 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid