磷酸化N-钙粘附分子抗体
规格:1mg/1ml
英文名: phospho-N Cadherin (Tyr820)
别名: N Cadherin (phospho Y820); p-CDH2 (Tyr820); CDH2 (phospho-Tyr820); CDH2 (phospho-T820); phospho-CDH2 (Tyr820); Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadher
分子量: 82kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞膜
磷酸化N-钙粘附分子抗体产品介绍:background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic磷酸化N-钙粘附分子抗体 manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. Subcellular Location: Cell membrane. Similarity: Contains 5 cadherin domains. Gene ID: 1000 Database links: Entrez Gene: 1000 Human Entrez Gene: 12558 Mouse Entrez Gene: 83501 磷酸化N-钙粘附分子抗体Rat Omim: 114020 Human SwissProt: P19022 Human SwissProt: P15116 Mouse SwissProt: Q9Z1Y3 Rat Unigene: 464829 Human Unigene: 606106 Human Unigene: 257437 Mouse Unigene: 23200 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. N-钙粘附分子属于依赖钙离子的细胞间糖蛋白粘附分子的一部分,主要是参与细胞间同源性粘附,调控和介导细胞间相互反应。
磷酸化N-钙粘附分子抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid