磷酸化自噬相关蛋白9A抗体
规格:1mg/1ml
英文名: phospho-ATG9A(Ser735)
别名: APG9 autophagy 9-like 1; APG9 like 1; APG9-like 1; APG9L1; ATG9; ATG9 autophagy related 9 homolog A; ATG9 autophagy related 9 homolog A (S. cerevisiae); ATG9A; ATG9A_HUMAN; Autophagy 9-like 1 protein;
分子量: 94kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Pig, Cow,
细胞定位:
磷酸化自噬相关蛋白9A抗体产品介绍:background: Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A. Function: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces 磷酸化自噬相关蛋白9A抗体accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H. Subunit: Interacts with SUPT20H. Subcellular Location: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear 磷酸化自噬相关蛋白9A抗体clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1. Similarity: Belongs to the ATG9 family. Database links: UniProtKB/Swiss-Prot: Q7Z3C6.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化自噬相关蛋白9A抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 **学 神经生物学 信号转导 细胞凋亡 线粒体 泛素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid