核基质蛋白3抗体
规格：1mg/1ml
英文名： Matrin 3
别名： MATR3; Matrin3; Matrin-3; KIAA0723; Matr3; MATR3_HUMAN; MPD2; VCPDM.
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Matrin 3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
核基质蛋白3抗体产品介绍：background: Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3. The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene. Function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Subunit: Part of complex consisting核基质蛋白3抗体 of SFPQ, NONO and MATR3. Interacts with EIF2C1 and EIF2C2. Subcellular Location: Nucleus matrix. DISEASE: Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders. Similarity: Contains 1 matrin-type zinc finger. Contains 2 RRM (RNA recognition motif) domains. Database links: 核基质蛋白3抗体Entrez Gene: 9782 Human Entrez Gene: 17184 Mouse Entrez Gene: 29150 Rat Omim: 164015 Human SwissProt: P43243 Human SwissProt: Q8K310 Mouse SwissProt: P43244 Rat Unigene: 268939 Human Unigene: 595110 Human Unigene: 215034 Mouse Unigene: 482118 Mouse Unigene: 29774 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核基质蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 染色质和核信号 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid