F肌动蛋白α2亚基抗体
规格:1mg/1ml
英文名: CAPZA2
别名: CAPPA2; CapZ alpha 2; Capping protein (actin filament) muscle Z line, alpha 2; CapZ alpha 2; CAPZ; F actin capping protein subunit alpha 2; CAZA2_HUMAN.
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CapZ alp
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:
F肌动蛋白α2亚基抗体产品介绍:background: The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008] Function: F-actin-capping proteins bind in a Ca(2+)-independentmanner to the fast growing ends of actin filaments (barbed end)thereby blocking the exchange of subunits at these ends. Unlikeother capping proteins (such as gelsolin and severin), theseproteins do not sever actin filaments. Subunit: Heterodimer of an alpha and a beta F肌动蛋白α2亚基抗体subunit. Component ofthe WASH complex, composed of F-actin-capping protein subunit alpha(CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta(CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P),FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.Interacts with RCSD1/CAPZIP. Similarity: Belongs to the F-actin-capping protein alpha subunitfamily. Database links: Entrez Gene: 830 Human Entrez Gene: 493728 Cow Entrez Gene: 503863 Dog Entrez Gene: 12343 Mouse Entrez Gene: 493810 RatF肌动蛋白α2亚基抗体 Omim: 601571 Human SwissProt: Q5E997 Cow SwissProt: A0M8V0 Dog SwissProt: P47755 Human SwissProt: P47754 Mouse SwissProt: Q3T1K5 Rat Unigene: 446123 Human Unigene: 392504 Mouse Unigene: 17868 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产F肌动蛋白α2亚基抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid