线粒体蛋白酪氨酸磷酸酶1/DUSP23抗体
规格：1mg/1ml
英文名： PTPMT1
别名： DUSP23; FLJ46081; MOSP; NB4 apoptosis/differentiation related protein; Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Phosphoinositide lipid phosphatase; PLIP; PNAS 129; protein ty
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PTPMT1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆 细胞膜 线粒体
线粒体蛋白酪氨酸磷酸酶1/DUSP23抗体产品介绍：background: This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells. Function: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on 线粒体蛋白酪氨酸磷酸酶1/DUSP23抗体Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity). Subcellular Location: Mitochondrion inner membrane. Note=Associated with the inner membrane. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein 线粒体蛋白酪氨酸磷酸酶1/DUSP23抗体phosphatase domain. Database links: Entrez Gene: 114971 Human Entrez Gene: 483622 Dog Omim: 609538 Human SwissProt: Q8WUK0 Human Unigene: 656205 Human Unigene: 728160 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体蛋白酪氨酸磷酸酶1/DUSP23抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子 激酶和磷酸酶 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid