胸腺表达趋化因子抗体
规格：1mg/1ml
英文名： TECK
别名： A130072A22Rik; C-C motif chemokine 25; CCL 25; CCL25; CCL25_HUMAN; Chemokine (C C motif) ligand 25; Chemokine (CC motif) ligand 25; Chemokine C C motif ligand 25; Chemokine CC motif ligand 25; Chemoki
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCL25
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：分泌型蛋白
胸腺表达趋化因子抗体产品介绍：background: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TECK displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. TECK binds to chemokine receptor CCR9. Two alternatively spliced variants encoding two different isoforms have been identified. Function: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes,胸腺表达趋化因子抗体 macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Subcellular Location: Secreted. Tissue Specificity: Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene:胸腺表达趋化因子抗体 6370 Human Omim: 602565 Human SwissProt: O15444 Human Unigene: 310511 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胸腺表达趋化因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 趋化因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid