单酰甘油脂肪酶抗体
规格:1mg/1ml
英文名: Monoacylglycerol Lipase
别名: HU K5; HUK5; Lysophospholipase homolog; Lysophospholipase like; MAGL; MGLL; Monoglyceride lipase; EC 3.1.1.23; MGLL_HUMAN.
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Monoacyl
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:
单酰甘油脂肪酶抗体产品介绍:background: Endocannaboids such as arachidonoyl ethanolamide and 2-arachidonoyl glycerol function as short range modulators of cell and synaptic activity. Monoacylglycerol lipase hydrolyzes 2-arachidonoyl glycerol which terminates it's biological actions. Monoacylglycerol lipase also works consecutively with hormone sensitive lipase to mobilize fatty acids from triglyceride stores of adipocytes. Monoacylglycerol lipase is expressed in kidney, spleen, heart, liver, testis, stomach, brain and lung tissue, and adrenal gland. It is most abundantly expressed in skeletal muscle and adipose tissue. Function: Converts monoacylglycerides to free fatty acids and glycerol.单酰甘油脂肪酶抗体 Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. Subunit: Homodimer. Tissue Specificity: Detected in adipose tissue, lung, liver, kidney, brain and heart. Similarity: Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. Gene ID: 11343 Database links: Entrez Gene: 505290单酰甘油脂肪酶抗体 Cow Entrez Gene: 11343 Human Entrez Gene: 23945 Mouse Entrez Gene: 29254 Rat Omim: 609699 Human SwissProt: Q99685 Human SwissProt: O35678 Mouse SwissProt: Q8R431 Rat Unigene: 277035 Human Unigene: 272197 Mouse Unigene: 40396 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
单酰甘油脂肪酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid