胆固醇24羟化酶抗体
规格：1mg/1ml
英文名： CYP46
别名： Cholesterol 24-hydroxylase; CP46; CYP46; cytochrome P450 family 46; CP46A_HUMAN.
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CYP46
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
胆固醇24羟化酶抗体产品介绍：background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008] Function: Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein.胆固醇24羟化酶抗体 Microsome membrane; Single-pass membrane protein. Tissue Specificity: Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample胆固醇24羟化酶抗体 but its expression increases linearly with age. Similarity: Belongs to the cytochrome P450 family. Gene ID: 10858 Database links: Entrez Gene: 10858 Human Entrez Gene: 13116 Mouse Entrez Gene: 362782 Rat Omim: 604087 Human SwissProt: Q9Y6A2 Human SwissProt: Q9WVK8 Mouse Unigene: 25121 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胆固醇24羟化酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid