醛固酮还原酶家族1成员D1抗体
规格：1mg/1ml
英文名： AKR1D1
别名： 3-oxo-5-beta-steroid 4-dehydrogenase; 3o5bred; AK1D1_HUMAN; AKR1D1; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase); Aldo keto reductase family 1 member D1; Aldo-keto r
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AKR1D1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：
醛固酮还原酶家族1成员D1抗体产品介绍：background: Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates. Function: Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates. Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in liver. Expressed in testis and weakly in colon. DISEASE: Congenital bile acid synthesis defect 2 (CBAS2) 醛固酮还原酶家族1成员D1抗体[MIM:235555]: A condition characterized by jaundice, intrahepatic cholestasis and hepatic failure. Patients with this liver disease show absence or low levels of chenodeoxycholic acid and cholic acid in plasma and urine. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the aldo/keto reductase family. Gene ID: 6718 Database links: Entrez Gene: 醛固酮还原酶家族1成员D1抗体6718 Human Entrez Gene: 208665 Mouse Omim: 604741 Human SwissProt: P51857 Human SwissProt: Q8VCX1 Mouse Unigene: 201667 Human Unigene: 740214 Human Unigene: 262635 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
醛固酮还原酶家族1成员D1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid