胚胎干细胞RAS蛋白抗体
规格：1mg/1ml
英文名： ERAS
别名： E ras; E-Ras; ecat5; Embryonic stem cell expressed Ras; Embryonic stem cell-expressed Ras; Eras; ES cell expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRASP; MGC126691; MGC126693; OTTHUMP00000065857; RA
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ERAS/HRA
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
胚胎干细胞RAS蛋白抗体细胞定位：细胞浆 细胞膜
产品介绍：background: ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase. Function: Ras proteins bind GDP/GTP and possess intrinsic胚胎干细胞RAS蛋白抗体 GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity). Subunit: Interacts with PIK3CD (By similarity). Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Similarity: Belongs to the small GTPase superfamily. Ras family. Database links: Entrez Gene: 3266 Human Entrez Gene: 353283 Mouse Entrez Gene: 679682 Rat Omim: 300437 胚胎干细胞RAS蛋白抗体Human SwissProt: Q7Z444 Human SwissProt: Q7TN89 Mouse Unigene: 447330 Human Unigene: 250895 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胚胎干细胞RAS蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学 染色质和核信号 信号转导 干细胞 G蛋白偶联受体 细胞表面分子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid