胰岛β细胞生长因子Reg IIIα 抗体
规格:1mg/1ml
英文名: Reg3 beta
别名: Pap; Pap1; REG3B_MOUSE; Regenerating islet-derived protein 3-beta; REG-3-beta; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-beta; Reg III-beta.
分子量: 16kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from mouse Reg3 bet
交叉反应:Mouse, Rat,
细胞定位:分泌型蛋白
胰岛β细胞生长因子Reg IIIα 抗体产品介绍:background: The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Specifically, increased expression of Reg III Alpha results in pancreatic inflammation and liver carcinogenesis. Reg III Alpha, also de-signated pancreatitis-associated protein, localizes to the apical region of pancreatic acinar cells and is similar to the C-type lectin superfamily. The Reg III Alpha 胰岛β细胞生长因子Reg IIIα 抗体protein is mainly expressed in the intestine, with lower expression detected in healthy pancreas. It is also detected in pancreatic juice as a result of pancreatic inflammation. Function: Might be a stress protein involved in the control of bacterial proliferation. Subcellular Location: Secreted. Found in the apical region of pancreatic acinar cells. Tissue Specificity: Constitutively expressed in the small intestine, 胰岛β细胞生长因子Reg IIIα 抗体moderately in colon and at an extremely low level in healthy pancreas. DISEASE: Note=Overexpressed during the acute phase of pancreatitis. Similarity: Contains 1 C-type lectin domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛β细胞生长因子Reg IIIα 抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid