**肽CAMP抗体
规格：1mg/1ml
英文名： Cathelicidin
别名： 18 kDa cationic antimicrobial protein; Antibacterial protein FALL-39; Antibacterial protein LL-37; CAMP; CRAMP_MOUSE; CAP 18; CAP-18; CAP18; cathelicidin antimicrobial peptide; Cathelicidin antimicrob
分子量： 4kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse Cathelic
交叉反应：Mouse, Rat,
细胞定位：分泌型蛋白
**肽CAMP抗体产品介绍：background: Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in ∫-pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related **肽CAMP抗体antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine. Function: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Subcellular Location: Secreted. Tissue Specificity: Expressed in bone marrow and testis and neutrophils. Similarity: Belongs to the cathelicidin family. Gene ID: 12796 Database links: Entrez Gene: 741881 Chimpanzee Entrez Gene: 820 Human Entrez Gene: 12796 Mouse Entrez Gene: 619186 Rhesus monkey Omim:**肽CAMP抗体 600474 Human SwissProt: Q1KLY6 African Green Monkey SwissProt: Q1KLX1 Chimpanzee SwissProt: Q1KLX7 Cynomolgus Monkey SwissProt: Q1KLY3 Gorilla SwissProt: P49913 Human SwissProt: Q1KLX6 Macaque Monkey SwissProt: P51437 Mouse SwissProt: Q1KLX2 Orangutan SwissProt: Q9GLV5 Rhesus monkey Unigene: 51120 Human Unigene: 3834 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**肽CAMP抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 微生物学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid