磷酸化糖原合酶激酶-3α抗体
规格：1mg/1ml
英文名： phospho-GSK3 Alpha(Ser21)
别名： Gsk3a; Glycogen synthase kinase-3 alpha; GSK 3 alpha; DKFZp686D0638; GSK 3A; GSK3A; GSK3alpha.
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse,
细胞定位：
磷酸化糖原合酶激酶-3α抗体产品介绍：background: Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. 磷酸化糖原合酶激酶-3α抗体Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in磷酸化糖原合酶激酶-3α抗体 protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GSK-3α和GSK-3β，在细胞和组织中广泛存在，参与多个信号通路的排列，包括糖原合成和细胞黏附作用。
产磷酸化糖原合酶激酶-3α抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid