Muellerian缪勒管**抑制因子抗体
规格:1mg/1ml
英文名: AMH
别名: MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.
分子量: 57kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human AMH
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:分泌型蛋白
Muellerian缪勒管**抑制因子抗体产品介绍:background: Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]. Function: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. DISEASE: Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditismMuellerian缪勒管**抑制因子抗体 characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the TGF-beta family. Database links: Muellerian缪勒管**抑制因子抗体Entrez Gene: 268 Human Entrez Gene: 11705 Mouse Entrez Gene: 25378 Rat Omim: 600957 Human SwissProt: P03971 Human SwissProt: P27106 Mouse SwissProt: P49000 Rat Unigene: 112432 Human Unigene: 19121 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Muellerian缪勒管**抑制因子抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 信号转导 干细胞 生长因子和** 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid