含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族10抗体
规格:1mg/1ml
英文名: ASB10
别名: Ankyrin repeat and SOCS box containing 10; Ankyrin repeat and SOCS box protein 10; ASB 10; ASB-10; ASB10; ASB10_HUMAN.
分子量: 51kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ASB10.
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族10抗体产品介绍:background: ASB10 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling (SOCS) family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box couples the suppressor of cytokine signalling proteins and their binding partners with the elongin B and C complex, 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族10抗体possibly targeting them for degradation. Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族10抗体 and subsequent proteasomal degradation of target proteins (By similarity). Similarity: Contains 7 ANK repeats. Contains 1 SOCS box domain. Database links: UniProtKB/Swiss-Prot: Q8WXI3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族10抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid