磷脂酶B1膜相关蛋白抗体
规格:1mg/1ml
英文名: PLB1
别名: hPLB ; Lysophospholipase ; Phospholipase A2 ; Phospholipase B ; Phospholipase B/lipase ; Phospholipase B1 ; Phospholipase B1 membrane associated ; PLB 1 ; PLB ; PLB/LIP.
分子量: 163kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PLB1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
磷脂酶B1膜相关蛋白抗体产品介绍:background: PLB1 is a membrane-associated phospholipase which exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. It shows preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. It also exhibits esterase activity toward p-nitrophenyl. It may act on the brush border membrane to facilitate the absorption of digested lipids. Function: Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis 磷脂酶B1膜相关蛋白抗体at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). Subcellular Location: Apical cell membrane; Single-pass type I membrane protein. Note: Present in the intestinal brush border membranes.磷脂酶B1膜相关蛋白抗体 Tissue Specificity: Expressed in the epidermis (at protein level). Post-translational modifications: Undergoes proteolytic cleavage in the ileum. Similarity: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily. Database links: Entrez Gene: 151056 Human Omim: 610179 Human SwissProt: Q6P1J6 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷脂酶B1膜相关蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid