硬纤毛蛋白STRC抗体
规格：1mg/1ml
英文名： STRC
别名： DFNB16; Stereocilin; STRC; STRC_HUMAN.
分子量： 193kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human STRC
交叉反应：Human, Mouse, Rat,
细胞定位：
硬纤毛蛋白STRC抗体产品介绍：background: This gene encodes a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. [provided by RefSeq, Jul 2008] Function: Essential to the formation of horizontal top connectors between outer hair cell stereocilia. Subcellular Location: Cell surface. Associated with the hair bundle. DISEASE: Defects in STRC are the cause of deafness 硬纤毛蛋白STRC抗体autosomal recessive type 16 (DFNB16) [MIM:603720]. DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Defects in STRC are a cause of deafness-infertility syndrome (DIS) [MIM:611102]. DIS is characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes. Similarity: Belongs to the stereocilin family. Database links硬纤毛蛋白STRC抗体: Entrez Gene: 161497 Human Entrez Gene: 140476 Mouse Entrez Gene: 691937 Rat Omim: 606440 Human SwissProt: Q7RTU9 Human SwissProt: Q8VIM6 Mouse Unigene: 657395 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硬纤毛蛋白STRC抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid