脑源性磷酸酶PTPN18抗体
规格：1mg/1ml
英文名： PTPN18
别名： BDP 1; Brain derived phosphatase; Brain-derived phosphatase; Protein tyrosine phosphatase non receptor type 18; Protein tyrosine phosphatase non receptor type 18 brain derived; PTN18_HUMAN; PTP HSCF;
分子量： 50kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PTPN18
交叉反应：Human,
细胞定位：细胞核 细胞浆
脑源性磷酸酶PTPN18抗体产品介绍：background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] Function: Differentially脑源性磷酸酶PTPN18抗体 dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity: Expressed in brain, colon and several tumor-derived cell lines. Similarity: Belongs脑源性磷酸酶PTPN18抗体 to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 26469 Human Omim: 606587 Human SwissProt: Q99952 Human Unigene: 516390 Human Unigene: 726000 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑源性磷酸酶PTPN18抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid