NUDT15蛋白抗体
规格：1mg/1ml
英文名： NUDT15
别名： 8-dihydro-8-oxoguanine triphosphatase NUDT15; 8-oxo-dGTPase NUDT15; A730068G11Rik; EC 3.1.6.-; FLJ10956; MGC104352; MTH2; MutT homolog 2; Nucleoside diphosphate-linked moiety X motif 15; NUD15_HUMAN;
分子量： 19kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NUDT15
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
NUDT15蛋白抗体产品介绍：Function: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught theNUDT15蛋白抗体 interaction with PCNA. Similarity: Belongs to the Nudix hydrolase family. Contains 1 nudix hydrolase domain.NUDT15蛋白抗体 Gene ID: 55270 Database links: Entrez Gene: 55270 Human Entrez Gene: 214254 Mouse Entrez Gene: 290365 Rat SwissProt: Q9NV35 Human SwissProt: Q8BG93 Mouse Unigene: 144407 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NUDT15蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid