细胞生长抑制基因36蛋白抗体
规格：1mg/1ml
英文名： MGLAP/GIG36
别名： Cell growth inhibiting gene 36 protein; Cell growth-inhibiting gene 36 protein; GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX; GIG36; Matrix Gla protein; MGLAP; MGP; MGP_HUMAN; NTI.
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MGLAP/GI
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
细胞生长抑制基因36蛋白抗体产品介绍：background: The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Function: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. Subcellular Location: Secreted. Post-translational modifications: Requires vitamin K-dependent gamma-carboxylation for its function. DISEASE: Defects in MGP are the cause 细胞生长抑制基因36蛋白抗体of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. Similarity: Belongs to the osteocalcin/matrix 细胞生长抑制基因36蛋白抗体Gla protein family. Contains 1 Gla (gamma-carboxy-glutamate) domain. Database links: Entrez Gene: 4256 Human Omim: 154870 Human SwissProt: P08493 Human Unigene: 365706 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞生长抑制基因36蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid