5-羟色胺受体3B抗体
规格:1mg/1ml
英文名: 5HT3B receptor
别名: 5 HT3 B; 5 HT3B; 5 HTR3B; 5 hydroxytryptamine 3 receptor B subunit; 5 hydroxytryptamine receptor 3B; 5 hydroxytryptamine serotonin receptor 3B; 5-HT3-B; 5-HT3B; 5-HTR3B; 5-hydroxytryptamine 3 receptor
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human 5HTR3B/5
交叉反应:Human, Mouse, Rat, Cow, Rabbit,
细胞定位:细胞浆 细胞膜
5-羟色胺受体3B抗体产品介绍:background: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Subunit: Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.5-羟色胺受体3B抗体 Tissue Specificity: Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. Post-translational modifications: N-glycosylation required for membrane localization. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-羟色胺受体3B抗体5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily. Database links: Entrez Gene: 9177 Human Omim: 604654 Human SwissProt: O95264 Human Unigene: 241377 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-羟色胺受体3B抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 通道蛋白 G蛋白偶联受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid