产品资料
  首页 >>> 产品目录 >>> **学 >>> 单克隆抗体

NCK衔接蛋白2抗体

如果您对该产品感兴趣的话,可以
产品名称: NCK衔接蛋白2抗体
产品型号: Nck beta
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

NCK衔接蛋白2抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。NCK衔接蛋白2抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


NCK衔接蛋白2抗体  的详细介绍

NCK衔接蛋白2抗体

规格:1mg/1ml

英文名: Nck beta

别名: Cytoplasmic protein NCK2; NCK2; GRB4; Growth factor receptor bound protein 4; NCK adaptor protein 2; Nck-2; NCK2; NCK2_HUMAN; NCKbeta; Non-catalytic region of tyrosine kinase adaptor protein 2; Noncat

分子量: 43kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human NCK2/Nck

交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,

细胞定位:

NCK衔接蛋白2抗体产品介绍:background: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. Function: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation NCK衔接蛋白2抗体in response to activated Ras signaling. Subunit: Interacts with DOCK1, LIMS1 and TGFB1I1. Part of a complex containing PPP1R15B, PP1 and NCK2. Interacts with FASLG (By similarity). Interacts with AXL. Interacts with PAK1, PKN2 and SOS1. Interacts (via SH2 domain) with EGFR. Interacts (via SH2 domain) with DDR1. Subcellular Location: Cytoplasm. Endoplasmic reticulum. Tissue Specificity: NCK衔接蛋白2抗体Ubiquitous. Post-translational modifications: Phosphorylated. Similarity: Contains 1 SH2 domain. Contains 3 SH3 domains. Database links: Entrez Gene: 8440 Human Entrez Gene: 17974 Mouse Omim: 604930 Human SwissProt: O43639 Human SwissProt: O55033 Mouse Unigene: 529244 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NCK衔接蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  细胞生物  **学  染色质和核信号  信号转导  细胞周期蛋白  细胞类型标志物  细胞骨架  表观遗传学  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!