细胞周期蛋白依赖性激酶抑制剂2C抗体
规格:1mg/1ml
英文名: CDKN2C/p18 INK4c
别名: CDK6 inhibitor p18; CDKN 2C; CDKN 6; CDKN2C; CDKN6; CDN2C_HUMAN; Cyclin dependent inhibitor; Cyclin dependent kinase 4 inhibitor C; Cyclin dependent kinase 6 inhibitor; Cyclin dependent kinase 6 inhib
分子量: 18kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CDKN2C
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:
细胞周期蛋白依赖性激酶抑制剂2C抗体产品介绍:background: p18 INK4c is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart. Function: Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Subunit: Heterodimer of p18 with CDK6. Tissue Specificity: Highest levels found in skeletal muscle. Also found in pancreas and heart.细胞周期蛋白依赖性激酶抑制剂2C抗体 Similarity: Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. Contains 4 ANK repeats. Database links: Entrez Gene: 469319 Chimpanzee Entrez Gene: 505691 Cow Entrez Gene: 475359 Dog Entrez Gene: 101125732 Gorilla Entrez细胞周期蛋白依赖性激酶抑制剂2C抗体 Gene: 1031 Human Entrez Gene: 12580 Mouse Entrez Gene: 29658 Rat Entrez Gene: 711877 Rhesus monkey Omim: 603369 Human SwissProt: P42773 Human SwissProt: Q60772 Mouse Unigene: 525324 Human Unigene: 728783 Human Unigene: 1912 Mouse Unigene: 63865 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产细胞周期蛋白依赖性激酶抑制剂2C抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid