Notch配体Jagged 2蛋白抗体
规格:1mg/1ml
英文名: Jagged 2
别名: D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.
分子量: 134kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Jagged 2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位:细胞膜
Notch配体Jagged 2蛋白抗体产品介绍:background: Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2. Subcellular Location:Notch配体Jagged 2蛋白抗体 Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. Similarity: Contains 1 DSL domain. ContainsNotch配体Jagged 2蛋白抗体 16 EGF-like domains. Contains 1 VWFC domain. Database links: Entrez Gene: 3714 Human Entrez Gene: 16450 Mouse Entrez Gene: 29147 Rat Omim: 602570 Human SwissProt: Q9Y219 Human SwissProt: Q9QYE5 Mouse SwissProt: P97607 Rat Unigene: 433445 Human Unigene: 22459 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Notch配体Jagged 2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 神经生物学 干细胞 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid