尿苷二磷酸葡萄糖醛酸转移酶1A9
规格：1mg/1ml
英文名： UGT1A9
别名： GNT1; HLUGP4; LUGP4; UDP glucuronosyltransferase 1A9; UDPGT; UGT1I; UD19_HUMAN.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human UGT1A9
交叉反应：Human, Mouse, Rat,
细胞定位：
尿苷二磷酸葡萄糖醛酸转移酶1A9产品介绍：background: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols. Function: UDPGT is of major importance in the 尿苷二磷酸葡萄糖醛酸转移酶1A9conjugation and subsequent elimination of potentially toxic xenobiotics and 尿苷二磷酸葡萄糖醛酸转移酶1A9endogenous compounds. This isoform has specificity for phenols. Subcellular Location: Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein (Potential). Tissue Specificity: Liver. Similarity: Belongs to the UDP-glycosyltransferase family. Database links: UniProtKB/Swiss-Prot: O60656.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
尿苷二磷酸葡萄糖醛酸转移酶1A9产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid