蛋白酶体激活因子PA28γ抗体
规格：1mg/1ml
英文名： PSME3
别名： PA28G; 11S regulator complex gamma subunit; 11S regulator complex subunit gamma; Activator of multicatalytic protease subunit 3; Ki antibody Ki antigen; Ki nuclear autoantigen; Ki, PA28 gamma; PA28 ga
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PSME3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
蛋白酶体激活因子PA28γ抗体产品介绍：background: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a donut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-TP53/p53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of TP53/p53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Database links: Entrez Gene: 420017 Chicken Entrez Gene: 740582 蛋白酶体激活因子PA28γ抗体Chimpanzee Entrez Gene: 480512 Dog Entrez Gene: 101131213 Gorilla Entrez Gene: 10197 Human Entrez Gene: 19192 Mouse Entrez Gene: 100171504 Orangutan Entrez Gene: 397625 Pig Entrez Gene: 287716 Rat Entrez Gene: 494719 Xenopus laevis Entrez Gene: 100124751 Xenopus tropicalis Omim: 605129 Human SwissProt: Q5F3J5 Chicken SwissProt: P61289 Human SwissProt: P61290 Mouse SwissProt:蛋白酶体激活因子PA28γ抗体 Q5RFD3 Orangutan SwissProt: P61291 Pig Unigene: 152978 Human Unigene: 288477 Mouse Unigene: 198325 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酶体激活因子PA28γ抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 染色质和核信号 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid