硒结合蛋白1抗体
规格：1mg/1ml
英文名： Selenium Binding Protein 1
别名： 56 kDa selenium binding protein; 56 kDa selenium-binding protein; hSBP; LPSB; SBP; SBP1; SBP1_HUMAN; SBP56; Selenbp1; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium-binding
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SBP1/Sel
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞核 细胞浆 细胞膜
硒结合蛋白1抗体产品介绍：background: Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease. Function: Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. Subunit: Interacts with USP33. Subcellular Location: Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes. 硒结合蛋白1抗体Tissue Specificity: Present in liver and colon (at protein level). Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the selenium-binding protein family. Database links: Entrez Gene: 8991 Human Entrez Gene: 20341 Mouse Entrez Gene: 140927 硒结合蛋白1抗体Rat Omim: 604188 Human SwissProt: Q13228 Human SwissProt: P17563 Mouse SwissProt: Q8VIF7 Rat Unigene: 632460 Human Unigene: 16617 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid