整合素样金属蛋白酶与凝血酶4型抗体
规格：1mg/1ml
英文名： ADAMTS4
别名： ADAMTS 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4; A disintegrin like and metallop
分子量： 90kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ADAMTS4
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位：分泌型蛋白
整合素样金属蛋白酶与凝血酶4型抗体产品介绍：background: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu- -Ala-393' site. Subcellular Location: Secreted > extracellular space > 整合素样金属蛋白酶与凝血酶4型抗体extracellular matrix. Tissue Specificity: Expressed in brain, lung and heart. Expressed at very low level in placenta and skeletal muscles. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Contains整合素样金属蛋白酶与凝血酶4型抗体 1 disintegrin domain. Contains 1 peptidase M12B domain. Contains 1 TSP type-1 domain. Gene ID: 9507 Database links: Entrez Gene: 9507 Human Entrez Gene: 240913 Mouse Omim: 603876 Human SwissProt: O75173 Human SwissProt: Q8BNJ2 Mouse Unigene: 211604 Human Unigene: 475917 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
整合素样金属蛋白酶与凝血酶4型抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid