非受体型蛋白酪氨酸磷酸酶7抗体
规格：1mg/1ml
英文名： PTPN7
别名： HePTP; BPTP 4; BPTP4; Dual specificity phosphatase 1; Hematopoietic protein tyrosine phosphatase; LC PTP; LCPTP; LPTP; Protein tyrosine phoshatase non receptor type stress induced; Protein tyrosine ph
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PTPN7
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞浆
非受体型蛋白酪氨酸磷酸酶7抗体产品介绍：background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. 非受体型蛋白酪氨酸磷酸酶7抗体[provided by RefSeq]. Function: Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction. Subunit: Monomer. Interacts with MAPK1, MAPK3 and several other MAP kinases. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed exclusively in thymus and spleen. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: 非受体型蛋白酪氨酸磷酸酶7抗体Entrez Gene: 5778 Human Entrez Gene: 320139 Mouse Entrez Gene: 246781 Rat Omim: 176889 Human SwissProt: P35236 Human SwissProt: Q8BUM3 Mouse SwissProt: P49445 Rat Unigene: 402773 Human Unigene: 258388 Mouse Unigene: 10160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产非受体型蛋白酪氨酸磷酸酶7抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid