酪氨酸磷酸酶α抗体
规格:1mg/1ml
英文名: PTPRA
别名: HEPTP; HLPR; HPTP alpha; HPTPA; HPTPalpha; Leukocyte common antigen related peptide; LRP; Protein tyrosine phosphatase alpha; Protein tyrosine phosphatase receptor type A; Protein tyrosine phosphatase
分子量: 89kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PTPRA
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位:
酪氨酸磷酸酶α抗体产品介绍:background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene,酪氨酸磷酸酶α抗体 which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. Contains 2 tyrosine-protein phosphatase domains. Database links: Entrez Gene: 5786 Human Entrez Gene: 19262 Mouse Entrez Gene: 25167 Rat Omim: 酪氨酸磷酸酶α抗体176884 Human SwissProt: P18433 Human SwissProt: P18052 Mouse SwissProt: Q03348 Rat Unigene: 269577 Human Unigene: 224246 Mouse Unigene: 18043 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酪氨酸磷酸酶α抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid