高尔基体膜蛋白GP73抗体
规格：1mg/1ml
英文名： GOLPH2
别名： Chromosome 9 open reading frame 155; Golgi membrane protein 1; Golgi membrane protein GP73; Golgi phosphoprotein 2; Golgi protein 73 kD; golgi protein 73kD; GOLM 1; GOLM1; GOLPH 2; GOLPH2; GP 73; GP73
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GOLPH2/G
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse,
细胞定位：细胞浆 细胞膜 细胞外基质
高尔基体膜蛋白GP73抗体产品介绍：background: GOLPH2 is widely expressed. Expression levels are high in the colon, prostate, trachea and stomach; expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. GOLPH2 is predominantly expressed by cells of the epithelial lineage. It is expressed at a low level in normal liver, though expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non viral causes (alcohol induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with ***** giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte derived syncitial giant cells. GOLPH2 is constitutively expressed by biliary epithelial cells but not by hepatocytes. Function: Unknown. Cellular response protein to viral infection. Subcellular Location: Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption. Tissue Specificity: Widely expressed. 高尔基体膜蛋白GP73抗体Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients 高尔基体膜蛋白GP73抗体with ***** giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. Similarity: Belongs to the GOLM1/CASC4 family. Gene ID: 51280 Database links: Entrez Gene: 51280 Human Entrez Gene: 105348 Mouse Entrez Gene: 306725 Rat Omim: 606804 Human SwissProt: Q8NBJ4 Human SwissProt: Q91XA2 Mouse Unigene: 494337 Human Unigene: 171335 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
高尔基体膜蛋白GP73抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 染色质和核信号 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid