磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体
规格：1mg/1ml
英文名： phospho-MYL9 (Thr19)
别名： MYL9 (phospho T19); p-MLC(Thr19); phospho-MLC(Thr19); p-Myosin light chain(Thr19); Myosin light chain (phospho T19); MYL9_HUMAN; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20;
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：
磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体产品介绍：background: MYL9 is the myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. MYL9 protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for MYL9 and the deduced 172-amino acid protein is highly conserved, with only 3 differences between the human and chicken proteins. Light chain phosphorylation causes the folded monomeric form of myosin to extend and assemble into filaments. This observation established the involvement of the MYL9 in conformational transitions of smooth muscle myosin. Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Subunit: Myosin is a hexamer of 2 heavy chains and 磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体4 light chains. Tissue Specificity: Smooth muscle tissues and in some, but not all, nonmuscle cells. Post-translational modifications: Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge (By similarity).磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体 Similarity: Contains 3 EF-hand domains. Gene ID: 10398 Database links: Entrez Gene: 10398 Human Entrez Gene: 98932 Mouse Entrez Gene: 296313 Rat Omim: 609905 Human SwissProt: P20689 Human SwissProt: P24844 Human SwissProt: Q9CQ19 Mouse SwissProt: Q64122 Rat Unigene: 504687 Human Unigene: 271770 Mouse Unigene: 228729 Rat Unigene: 6870 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化肌球蛋白调节多肽9(平滑肌亚型)抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid