G1氨基丁酸A型受体相似蛋白2抗体
规格：1mg/1ml
英文名： GABARAPL2
别名： ATG 8; ATG8; FLC 3A; FLC3A; GABA(A) receptor associated protein like 2; Gamma aminobutyric acid receptor associated protein like 2; Ganglioside expression factor 2; GATE 16; GATE16; General protein tr
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GABARAPL
交叉反应：Human, Mouse, Rat, Chicken, Cow, Rabbit,
细胞定位：细胞浆
G1氨基丁酸A型受体相似蛋白2抗体产品介绍：background: In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing (1). GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2,3). In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein) (4-6). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton (6). The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex (6). Function: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the G1氨基丁酸A型受体相似蛋白2抗体ATPase activity of NSF which in turn stimulates the association with GOSR1. Subcellular Location: Golgi apparatus. Tissue Specificity: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the MAP1 LC3 family. Database links: Entrez Gene: 11345 Human Entrez Gene: 93739 Mouse Entrez Gene: 100359937 Rat Entrez Gene: 64670 Rat G1氨基丁酸A型受体相似蛋白2抗体Omim: 607452 Human SwissProt: P60520 Human SwissProt: P60521 Mouse SwissProt: P60522 Rat Unigene: 461379 Human Unigene: 371666 Mouse Unigene: 120952 Rat Unigene: 64537 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GABAA受体相关蛋白相似蛋白2；GABA受体A型相关蛋白样2
G1氨基丁酸A型受体相似蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 染色质和核信号 神经生物学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid